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Anti-Human TASP1 Polyclonal Antibody

  • Cat. No.:RB9THP777014
  • Price:Negotiable
  • Clicks:243

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse, Human
TargetC20orf13, EC:3.4.25.-, TASP1, Taspase-1, Threonine aspartase 1, Threonine aspartase subunit alpha, Threonine aspartase subunit beta
ImmunogenE. coli - derived recombinant Human TASP1 (Gly42-Asn420).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ9H6P5
Background

Threonine aspartase 1 (TASP1) is a ~44 kDa protein. Protease responsible for KMT2A/MLL1 processing and activation. It also activates KMT2D/MLL2. Through substrate activation, it controls the expression of HOXA genes, and the expression of key cell cycle regulators including CCNA1, CCNB1, CCNE1 and CDKN2A.

1. Hsieh, JJ. et al. (2003) Cell 115, 293-303. PMID: 14636557
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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