| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse, Human |
| Target | C20orf13, EC:3.4.25.-, TASP1, Taspase-1, Threonine aspartase 1, Threonine aspartase subunit alpha, Threonine aspartase subunit beta |
| Immunogen | E. coli - derived recombinant Human TASP1 (Gly42-Asn420). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9H6P5 |
| Background | Threonine aspartase 1 (TASP1) is a ~44 kDa protein. Protease responsible for KMT2A/MLL1 processing and activation. It also activates KMT2D/MLL2. Through substrate activation, it controls the expression of HOXA genes, and the expression of key cell cycle regulators including CCNA1, CCNB1, CCNE1 and CDKN2A. 1. Hsieh, JJ. et al. (2003) Cell 115, 293-303. PMID: 14636557 |
| Note | For research use only |