Anti-Human ATRAID Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Human
Target	APR-3, APR3, ATRAID, All-trans retinoic acid-induced differentiation factor, Apoptosis-related protein 3, C2orf28, p18
Immunogen	E. coli - derived recombinant Human ATRAID (Leu31-Ser199).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q6UW56
Background	All-trans retinoic acid-induced differentiation factor (ATRAID) is a ~24 kDa protein. Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway. In osteoclasts, forms a transporter complex with ATRAID for nitrogen-containing-bisphophonates (N-BPs) required for releasing N-BP molecules that have trafficked to lysosomes through fluid-phase endocytosis into the cytosol. 1. Yu, Z. et al. (2018) eLife 7. PMID: 29745899
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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