| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | MADHIP, Madh-interacting protein, Mothers against decapentaplegic homolog-interacting protein, NSP, Novel serine protease, Receptor activation anchor, SARA, SMADIP, Smad anchor for receptor activation |
| Immunogen | E. coli - derived recombinant Human ZFYVE9 (Ile907-Val1425). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | O95405 |
| Background | Zinc finger FYVE domain-containing protein 9 (ZFYVE9) is a ~156 kDa protein. Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization. |
| Note | For research use only |