| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Mouse, Rat |
| Target | ALX homeobox protein 1, ALX1, CART-1, CART1, Cartilage homeoprotein 1 |
| Immunogen | E. coli - derived recombinant Human ALX1 (Arg136-Met326). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q15699 |
| Background | ALX homeobox protein 1 (ALX1) is a ~36 kDa protein. Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes. Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival. May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1. 1. Gordon, DF. et al. (1996) DNA and cell biology 15, 531-41. PMID: 8756334 2. Cai, RL. (1998) Biochemical and biophysical research communications 250, 305-11. PMID: 9753625 3. Uz, E. et al. (2010) American journal of human genetics 86, 789-96. PMID: 20451171 4. Yuan, H. et al. (2013) Cancer research 73, 1581-90. PMID: 23288509 |
| Note | For research use only |