Anti-Human ATXN7L3 Polyclonal Antibody
- Cat. No.：RB9THD670014
- Price：Negotiable
- Clicks：309
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Mouse |
| Target | ATXN7L3, Ataxin-7-like protein 3, SAGA-associated factor 11 homolog |
| Immunogen | E. coli - derived recombinant Human ATXN7L3 (Asp54-Val247). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q14CW9 |
| Background | Ataxin-7-like protein 3 (ATXN7L3) is a ~38 kDa protein. Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex. 1. Zhao, Y. et al. (2008) Molecular cell 29, 92-101. PMID: 18206972 2. Lang, G. et al. (2011) Molecular and cellular biology 31, 3734-44. PMID: 21746879 3. Li, W. et al. (2016) Molecular and cellular biology 36, 2855-2866. PMID: 27601583 |
| Note | For research use only |
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