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Anti-Human CEP250 Polyclonal Antibody

  • Cat. No.:RB9THD660014
  • Price:Negotiable
  • Clicks:180

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHuman
Target250 kDa centrosomal protein, C-Nap1, CEP2, CEP250, CNAP1, Centrosomal Nek2-associated protein 1, Centrosomal protein 2, Centrosome-associated protein CEP250, Cep250
ImmunogenE. coli - derived recombinant Human CEP250 (Arg40-Thr293).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ9BV73
Background

Centrosome-associated protein CEP250 is a ~281 kDa protein. Plays an important role in centrosome cohesion during interphase. Recruits CCDC102B to the proximal ends of centrioles. Maintains centrosome cohesion by forming intercentriolar linkages. Accumulates at the proximal end of each centriole, forming supramolecular assemblies with viscous material properties that promote organelle cohesion. May be involved in ciliogenesis.

1. Xia, Y. et al. (2018) Journal of cell science 131. PMID: 30404835
2. Mahen, R. (2022) PLoS biology 20, e3001854. PMID: 36282799
3. de Castro-Miró, M. et al. (2016) PloS one 11, e0168966. PMID: 28005958
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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