Anti-Human NHERF-3/PDZK1 Polyclonal Antibody
- Cat. No.：RB9THA122014
- Price：Negotiable
- Clicks：212
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | CAP70, CFTR-associated protein of 70 kDa, NHERF-3, NHERF3, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Na(+)/H(+) exchanger regulatory factor 3, Na/Pi cotransporter C-terminal-associated protein |
| Immunogen | E. coli - derived recombinant Human NHERF-3/PDZK1 (Met1-Ser341). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q5T2W1 |
| Background | Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (NHERF-3/PDZK1) is a ~57 kDa protein. A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with NHERF1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. |
| Note | For research use only |
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