| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | C20orf155, CLS, CLS1, CRLS1, Cardiolipin synthase (CMP-forming), EC:2.7.8.41, Protein GCD10 homolog |
| Immunogen | E. coli - derived recombinant Human CRLS1 (Leu2-Thr108). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9UJA2 |
| Background | Cardiolipin synthase (CMP-forming) (CRLS1) is a ~32 kDa protein. Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. 1. Lu, B. et al. (2006) Journal of lipid research 47, 1140-5. PMID: 16547353 2. Houtkooper, RH. et al. (2006) FEBS letters 580, 3059-64. PMID: 16678169 3. Chen, D. et al. (2006) The Biochemical journal 398, 169-76. PMID: 16716149 4. Lee, RG. et al. (2022) Human molecular genetics 31, 3597-3612. PMID: 35147173 |
| Note | For research use only |