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Anti-Human CRLS1 Polyclonal Antibody

  • Cat. No.:RB9THD659014
  • Price:Negotiable
  • Clicks:354

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHuman
TargetC20orf155, CLS, CLS1, CRLS1, Cardiolipin synthase (CMP-forming), EC:2.7.8.41, Protein GCD10 homolog
ImmunogenE. coli - derived recombinant Human CRLS1 (Leu2-Thr108).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ9UJA2
Background

Cardiolipin synthase (CMP-forming) (CRLS1) is a ~32 kDa protein. Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.

1. Lu, B. et al. (2006) Journal of lipid research 47, 1140-5. PMID: 16547353
2. Houtkooper, RH. et al. (2006) FEBS letters 580, 3059-64. PMID: 16678169
3. Chen, D. et al. (2006) The Biochemical journal 398, 169-76. PMID: 16716149
4. Lee, RG. et al. (2022) Human molecular genetics 31, 3597-3612. PMID: 35147173
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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