Anti-Human EFTUD2 Polyclonal Antibody
- Cat. No.：RB9THD650014
- Price：Negotiable
- Clicks：319
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Mouse |
| Target | 116 kDa U5 small nuclear ribonucleoprotein component, EFTUD2, Elongation factor Tu GTP-binding domain-containing protein 2, KIAA0031, SNRP116, SNU114 homolog, U5 snRNP-specific protein, 116 kDa, U5-11 |
| Immunogen | E. coli - derived recombinant Human EFTUD2 (Thr661-Met972). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q15029 |
| Background | 116 kDa U5 small nuclear ribonucleoprotein component (EFTUD2) is a ~109 kDa protein. Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes. Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). 1. Oka, Y. et al. (2014) EMBO reports 15, 956-64. PMID: 25092792 2. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346 3. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770 4. Bertram, K. et al. (2017) Cell 170, 701-713.e11. PMID: 28781166 5. Zhan, X. et al. (2018) Science (New York, N.Y.) 359, 537-545. PMID: 29301961 6. Zhang, X. et al. (2018) Cell research 28, 307-322. PMID: 29360106 7. Haselbach, D. et al. (2018) Cell 172, 454-464.e11. PMID: 29361316 8. Zhan, X. et al. (2018) Cell research 28, 1129-1140. PMID: 30315277 9. Fica, SM. et al. (2019) Science (New York, N.Y.) 363, 710-714. PMID: 30705154 10. Liu, S. et al. (2006) RNA (New York, N.Y.) 12, 1418-30. PMID: 16723661 |
| Note | For research use only |
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