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Anti-Human TRABD2A Polyclonal Antibody

  • Cat. No.:RB9THA378024
  • Price:Negotiable
  • Clicks:248

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHuman
TargetC2orf89, EC:3.4.-.-, Metalloprotease TIKI1, TIKI1, TRAB domain-containing protein 2A, TRABD2A
ImmunogenE. coli - derived recombinant Human TRABD2A (Ala20-His360).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ86V40
Background

Metalloprotease TIKI1 (TRABD2A) is a ~57 kDa protein. Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.

NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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