Anti-Human POLG2 Polyclonal Antibody
- Cat. No.：RB9THD645014
- Price：Negotiable
- Clicks：202
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | DNA polymerase gamma accessory 55 kDa subunit, DNA polymerase subunit gamma-2, MTPOLB, Mitochondrial DNA polymerase accessory subunit, MtPolB, POLG2, PolG-beta, p55 |
| Immunogen | E. coli - derived recombinant Human POLG2 (Arg182-Val485). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9UHN1 |
| Background | DNA polymerase subunit gamma-2 (POLG2) is a ~54 kDa protein. Accessory subunit of DNA polymerase gamma solely responsible for replication of mitochondrial DNA (mtDNA). Acts as an allosteric regulator of the holoenzyme activities. Enhances the polymerase activity and the processivity of POLG by increasing its interactions with the DNA template. Suppresses POLG exonucleolytic proofreading especially toward homopolymeric templates bearing mismatched termini. Binds to single-stranded DNA. |
| Note | For research use only |
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