Anti-Human GFM2 Polyclonal Antibody
- Cat. No.：RB9THD643014
- Price：Negotiable
- Clicks：501
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | EC:3.6.5.-, EF-G2mt, EFG2, Elongation factor G 2, mitochondrial, Elongation factor G2, GFM2, RRF2mt, Ribosome-releasing factor 2, mitochondrial, hEFG2, mEF-G 2 |
| Immunogen | E. coli - derived recombinant Human GFM2 (Ala461-Thr779). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q969S9 |
| Background | Ribosome-releasing factor 2, mitochondrial (GFM2) is a ~86 kDa protein. Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. Promotes mitochondrial ribosome recycling by dissolution of intersubunit contacts. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation. 1. Tsuboi, M. et al. (2009) Molecular cell 35, 502-10. PMID: 19716793 2. Kummer, E. et al. (2021) Molecular cell 81, 2566-2582.e6. PMID: 33878294 |
| Note | For research use only |
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