| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | CXorf5, Centriole and centriolar satellite protein OFD1, OFD1, Oral-facial-digital syndrome 1 protein, Protein 71-7A |
| Immunogen | E. coli - derived recombinant Human OFD1 (Ser15-Ser156). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | O75665 |
| Background | Centriole and centriolar satellite protein OFD1 is a ~116 kDa protein. Component of the centrioles controlling mother and daughter centrioles length. Recruits to the centriole IFT88 and centriole distal appendage-specific proteins including CEP164. Involved in the biogenesis of the cilium, a centriole-associated function. The cilium is a cell surface projection found in many vertebrate cells required to transduce signals important for development and tissue homeostasis. Plays an important role in development by regulating Wnt signaling and the specification of the left-right axis. 1. Senatore, E. et al. (2021) The EMBO journal 40, e106503. PMID: 33934390 |
| Note | For research use only |