Anti-Human GJA8 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Human
Target	Connexin-50, Cx50, GJA8, Gap junction alpha-8 protein, Lens fiber protein MP70
Immunogen	E. coli - derived recombinant Human GJA8 (Gly225-Val433).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	P48165
Background	Gap junction alpha-8 protein (GJA8) is a ~48 kDa protein. Structural component of eye lens gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore. 1. Arora, A. et al. (2008) Journal of medical genetics 45, 155-60. PMID: 18006672 2. Graw, J. et al. (2009) Molecular vision 15, 1881-5. PMID: 19756179
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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