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Anti-Human GJA8 Polyclonal Antibody

  • Cat. No.:RB9THD640014
  • Price:Negotiable
  • Clicks:334

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHuman
TargetConnexin-50, Cx50, GJA8, Gap junction alpha-8 protein, Lens fiber protein MP70
ImmunogenE. coli - derived recombinant Human GJA8 (Gly225-Val433).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberP48165
Background

Gap junction alpha-8 protein (GJA8) is a ~48 kDa protein. Structural component of eye lens gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore.

1. Arora, A. et al. (2008) Journal of medical genetics 45, 155-60. PMID: 18006672
2. Graw, J. et al. (2009) Molecular vision 15, 1881-5. PMID: 19756179
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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