Anti-Human CXCL17/DMC/VCC1 Polyclonal Antibody
- Cat. No.：RB9THV053014
- Price：Negotiable
- Clicks：305
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | 4-Cys CXCL17, 6-Cys CXCL17, C-X-C motif chemokine 17, CXCL17, DMC, Dendritic cell and monocyte chemokine-like protein, VCC1, VEGF coregulated chemokine 1 |
| Immunogen | E. coli - derived recombinant Human CXCL17/DMC/VCC1 (Ser22-Leu119). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q6UXB2 |
| Background | C-X-C motif chemokine 17 (CXCL17/DMC) is a ~13 kDa protein. Chemokine that acts as a chemoattractant for monocytes, macrophages and dendritic cells, and which is involved in immune regulation and lymphocyte trafficking. Activates the C-X-C chemokine receptor GPR25. Plays a key role in lymphocyte homing by activating the receptor GPR25 on lymphocytes, mediating lymphocyte recruitment into the respiratory, upper gastrointestinal, biliary and genito-urinary tracts. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach. 1. Pisabarro, MT. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 176, 2069-73. PMID: 16455961 2. Lee, WY. et al. (2013) American journal of physiology. Endocrinology and metabolism 304, E32-40. PMID: 23115081 3. Ocón, B. et al. (2024) Nature 635, 736-745. PMID: 39293486 4. Hu, WF. et al. (2025) The FEBS journal 292, 5998-6015. PMID: 40279398 5. Weinstein, EJ. et al. (2006) Biochemical and biophysical research communications 350, 74-81. PMID: 16989774 |
| Note | For research use only |
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