Anti-HBV HBsAg Polyclonal Antibody
- Cat. No.：RB9TVK539024
- Price：Negotiable
- Clicks：336
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Hepatitis B virus genotype B1, Hepatitis B virus genotype B2 subtype adw, Hepatitis B virus genotype B1 subtype adw, Hepatitis B virus genotype B2, Hepatitis B virus genotype B/C subtype adw |
| Target | L glycoprotein, L-HBsAg, LHB, Large S protein, Large envelope protein, Large surface protein, Major surface antigen, S |
| Immunogen | E. coli - derived recombinant HBV HBsAg (Met1-Arg253). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q67926 |
| Background | Large envelope protein (HBsAg) is a ~43 kDa protein. The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assures fusion between virion membrane and endosomal membrane. |
| Note | For research use only |
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