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Anti-HBV HBsAg Polyclonal Antibody

  • Cat. No.:RB9TVK539014
  • Price:Negotiable
  • Clicks:483

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHepatitis B virus genotype C, Hepatitis B virus genotype A1 subtype adw, Hepatitis B virus genotype C subtype ar, Hepatitis B virus genotype C subtype adr, Hepatitis B virus genotype C subtype ayr, He
TargetL glycoprotein, L-HBsAg, LHB, Large S protein, Large envelope protein, Large surface protein, Major surface antigen, S
ImmunogenE. coli - derived recombinant HBV HBsAg (Met1-Ile242).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberP03140
Background

Large envelope protein (HBsAg) is a ~43 kDa protein. The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assures fusion between virion membrane and endosomal membrane.

NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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