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Anti-CCHFV GP38 Polyclonal Antibody

  • Cat. No.:RB9TVK608044
  • Price:Negotiable
  • Clicks:342

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityCrimean-Congo hemorrhagic fever virus
Target15 kDa protein, 37 kDa protein, 75 kDa protein, Envelopment polyprotein, GP, GP38, Gc, Glycoprotein C, Glycoprotein G1, Glycoprotein G2, Glycoprotein N, Gn, M polyprotein, Mucin-like variable region,
ImmunogenE. coli - derived recombinant CCHFV GP38 (Asn248-Ser515).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ8JSZ3
Background

Envelopment polyprotein (GP38) is a ~186 kDa protein. Plays a role in virion attachment to host receptor. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis Glycoprotein N probably locks the Gn-Gc complex in a prefusion state.

1. Xu, ZS. et al. (2024) Cell research 34, 140-150. PMID: 38182887
2. Simon, M. et al. (2009) The Journal of general virology 90, 210-5. PMID: 19088291
3. Mishra, AK. et al. (2022) Science (New York, N.Y.) 375, 104-109. PMID: 34793197
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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