Anti-Yersinia enterocolitica sctE/YopB Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Yersinia pseudotuberculosis serotype I, Yersinia enterocolitica
Target	T3SS translocon protein SctE, Translocator YopB, Type 3 secretion system translocon protein SctE, Yersinia outer protein B, sctE, yopB
Immunogen	E. coli - derived recombinant Yersinia enterocolitica sctE/YopB (Gly246-Val401).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	P37131
Background	Type 3 secretion system translocon protein SctE (YopB) is a ~41 kDa protein. Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. YopB/SctE and YopD/SctB are inserted into the host membrane where they form a pore and allow the translocation of effector proteins into the cytosol of target cells. Is an essential virulence determinant. Required for YopE translocation. 1. Neyt, C. et al. (1999) Molecular microbiology 33, 971-81. PMID: 10476031 2. Tardy, F. et al. (1999) The EMBO journal 18, 6793-9. PMID: 10581252 3. Lee, VT. et al. (1999) Molecular microbiology 31, 1619-29. PMID: 10209737 4. Nordfelth, R. et al. (2001) Infection and immunity 69, 3516-8. PMID: 11292787
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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