| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Varicella-zoster virus |
| Target | 33, AP, Assemblin, Assembly protein, Capsid assembly protein, Capsid scaffolding protein, EC:3.4.21.97, Pr, Protease, Protease precursor, pPR |
| Immunogen | E. coli - derived recombinant VZV/HHV-3 Assemblin (Glu11-His231). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P09286 |
| Background | Capsid scaffolding protein (Assemblin) is a ~66 kDa protein. Acts as a scaffold protein by binding major capsid protein in the cytoplasm, inducing the nuclear localization of both proteins. Multimerizes in the nucleus such as major capsid protein forms the icosahedral T=16 capsid. Autocatalytic cleavage releases the assembly protein, and subsequently abolishes interaction with major capsid protein. Cleavages products are evicted from the capsid before or during DNA packaging. |
| Note | For research use only |