Anti-Human APOL1 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Human
Target	APOL, APOL1, Apo-L, ApoL, ApoL-I, Apolipoprotein L, Apolipoprotein L-I, Apolipoprotein L1
Immunogen	E. coli - derived recombinant Human APOL1 (Thr227-Leu398).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	O14791
Background	Apolipoprotein L1 (APOL1) is a ~43 kDa protein. May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. A component of trypanosome lytic factor of human serum; plays a crucial role in killing Trypanosoma brucei by forming pores in parasite lysosomal membranes and sensitizing T.brucei to oxidation-stimulated osmotic lysis. 1. Vanhamme, L. et al. (2003) Nature 422, 83-7. PMID: 12621437 2. Pérez-Morga, D. et al. (2005) Science (New York, N.Y.) 309, 469-72. PMID: 16020735 3. Lecordier, L. et al. (2009) PLoS pathogens 5, e1000685. PMID: 19997494 4. Greene, AS. et al. (2016) The Journal of biological chemistry 291, 3063-75. PMID: 26645690 5. Tytler, EM. et al. (1995) Molecular and biochemical parasitology 69, 9-17. PMID: 7723792
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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