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Anti-Human APOL1 Polyclonal Antibody

  • Cat. No.:RB9THT291014
  • Price:Negotiable
  • Clicks:196

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHuman
TargetAPOL, APOL1, Apo-L, ApoL, ApoL-I, Apolipoprotein L, Apolipoprotein L-I, Apolipoprotein L1
ImmunogenE. coli - derived recombinant Human APOL1 (Thr227-Leu398).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberO14791
Background

Apolipoprotein L1 (APOL1) is a ~43 kDa protein. May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. A component of trypanosome lytic factor of human serum; plays a crucial role in killing Trypanosoma brucei by forming pores in parasite lysosomal membranes and sensitizing T.brucei to oxidation-stimulated osmotic lysis.

1. Vanhamme, L. et al. (2003) Nature 422, 83-7. PMID: 12621437
2. Pérez-Morga, D. et al. (2005) Science (New York, N.Y.) 309, 469-72. PMID: 16020735
3. Lecordier, L. et al. (2009) PLoS pathogens 5, e1000685. PMID: 19997494
4. Greene, AS. et al. (2016) The Journal of biological chemistry 291, 3063-75. PMID: 26645690
5. Tytler, EM. et al. (1995) Molecular and biochemical parasitology 69, 9-17. PMID: 7723792
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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