Anti-HCV Envelope Glycoprotein E1 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Hepatitis C virus genotype 3a
Target	Capsid protein C, Core protein precursor, EC:2.7.7.48, EC:3.4.21.98, EC:3.4.22.-, EC:3.6.1.15, EC:3.6.4.13, Envelope glycoprotein E1, Envelope glycoprotein E2, Genome polyprotein, Hepacivirin, Mature
Immunogen	E. coli - derived recombinant HCV Envelope Glycoprotein E1 (Leu192-Gly358).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q81258
Background	Genome polyprotein (Envelope Glycoprotein E1) is a ~329 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication. Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable). 1. Jackel-Cram, C. et al. (2007) Journal of hepatology 46, 999-1008. PMID: 17188392
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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