| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Hepatitis B virus genotype B2 subtype adw, Hepatitis B virus genotype A2 subtype adw2, Gorilla hepatitis B virus, Chimpanzee hepatitis B virus, Hepatitis B virus genotype F2 subtype adw4q, Hepatitis B |
| Target | C, External core antigen, HBeAg, Precore protein, p25 |
| Immunogen | E. coli - derived recombinant HBV HBeAg (Ser20-Arg183). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P0C573 |
| Background | External core antigen (HBeAg) is a ~24 kDa protein. May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells. This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections. |
| Note | For research use only |