| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Aspergillus flavus |
| Target | EC:1.7.3.3, Rasburicase, Uox, Urate oxidase, Uricase, uaZ |
| Immunogen | E. coli - derived recombinant Aspergillus flavus Uricase (Met1-Leu302). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q00511 |
| Background | Uricase is a ~34 kDa protein. Urate oxidase is a cofactorless enzyme involved in the metabolism of purines (PubMed:1339455, PubMed:17020862, PubMed:28272834, Ref.3). Catalyzes, in the presence of molecular oxygen, the hydroxylation of uric acid to metastable 5-hydroxyisourate (5-HIU) which is further degraded to allantoin. 1. Legoux, R. et al. (1992) The Journal of biological chemistry 267, 8565-70. PMID: 1339455 2. Bayol, A. et al. (1995) Biophysical chemistry 54, 229-35. PMID: 17020862 3. Cheuk, DK. et al. (2017) The Cochrane database of systematic reviews 3, CD006945. PMID: 28272834 |
| Note | For research use only |