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Anti-RVFV Glycoprotein N/Gn Recombinant Antibody
- Cat. No.：RB9TVK101013
- Price：Negotiable
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Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Human |
| Clonality | Monoclonal |
| Isotype | IgG1, kappa |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, Neutralization, in vivo |
| Species Reactivity | Rift valley fever virus (RVFV) |
| Target | Envelopment polyprotein, GP, Glycoprotein G1, Glycoprotein N, Gn |
| Storage Buffer | 0.01M PBS pH 7.4 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping Condition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Accession Number | P21401 |
| Background | Envelopment polyprotein (Gn) is a ~130 kDa protein. Structural component of the virion that interacts with glycoprotein C. It shields the hydrophobic fusion loops of the glycoprotein C, preventing premature fusion. The glycoprotein protrusions are arranged on an icosahedral lattice, with T=12 triangulation. They are able to attach the virion to the host cell receptor CD209/DC-SIGN and to promote fusion of membranes with the late endosome after endocytosis of the virion. Plays a role in the packaging of ribonucleoproteins and polymerase during virus assembly. 1. Freiberg, AN. et al. (2008) Journal of virology 82, 10341-8. PMID: 18715915 2. Halldorsson, S. et al. (2018) Nature communications 9, 349. PMID: 29367607 3. Lozach, PY. et al. (2011) Cell host & microbe 10, 75-88. PMID: 21767814 4. Piper, ME. et al. (2011) PloS one 6, e18070. PMID: 21445316 |
| Note | For research use only |
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