Anti-Human Complement C5 Reference Antibody
- Cat. No.：RB9THF687196
- Price：Negotiable
- Clicks：441
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Human |
| Clonality | Monoclonal |
| Isotype | IgG H-gamma2-4 chimerisotype G2[11aaG4]-kappa |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin Level | < 10 EU/mg |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Species Reactivity | Human |
| Storage Buffer | 0.01 M PBS pH 7.4 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -82°C long term. |
| Product Usage Information | ELISA: 1:2000-1:20000 |
| Accession Number | P01031 |
| Background | Complement C5 (ComplementC5) is a ~188 kDa protein. Precursor of the C5a anaphylatoxin and complement C5b components of the complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Activated downstream of classical, alternative, lectin and GZMK complement pathways. 1. Rawal, N. et al. (2003) The Journal of biological chemistry 278, 38476-83. PMID: 12878586 2. Rawal, N. et al. (2008) The Journal of biological chemistry 283, 7853-63. PMID: 18204047 3. Heesterbeek, DA. et al. (2019) The EMBO journal 38. PMID: 30643019 4. DiScipio, RG. et al. (1983) The Journal of biological chemistry 258, 10629-36. PMID: 6554279 5. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456 6. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882 |
| Note | For research use only. |
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