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Anti-Human EREG/Epiregulin Reference Antibody

  • Cat. No.:RB9THT389016
  • Price:Negotiable
  • Clicks:422

Product Detail

Product Parameters

FormLiquid
Host SpeciesHuman
ClonalityMonoclonal
IsotypeIgG4, kappa
Purity>95% as determined by SDS-PAGE.
PurificationProtein A/G purified from cell culture supernatant.
Endotoxin Level< 10 EU/mg
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Species ReactivityHuman
Storage Buffer0.01 M PBS pH 7.4
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Product Usage InformationELISA: 1:2000-1:20000
Accession NumberO14944
Background

Proepiregulin (EREG) is a ~19 kDa protein. Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation. Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation.

1. Komurasaki, T. et al. (1997) Oncogene 15, 2841-8. PMID: 9419975
2. Riese, DJ. et al. (2014) Seminars in cell & developmental biology 28, 49-56. PMID: 24631357
NoteFor research use only.
For Research Use Only. Not for Diagnostic Procedures.

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