| Form | Liquid |
|---|---|
| Host Species | Human |
| Clonality | Monoclonal |
| Isotype | IgG4, kappa |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin Level | < 10 EU/mg |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Species Reactivity | Human |
| Storage Buffer | 0.01 M PBS pH 7.4 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Product Usage Information | ELISA: 1:2000-1:20000 |
| Accession Number | O14944 |
| Background | Proepiregulin (EREG) is a ~19 kDa protein. Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation. Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation. 1. Komurasaki, T. et al. (1997) Oncogene 15, 2841-8. PMID: 9419975 2. Riese, DJ. et al. (2014) Seminars in cell & developmental biology 28, 49-56. PMID: 24631357 |
| Note | For research use only. |