Anti-CRTC2 Polyclonal Antibody
- Cat. No.：RB9THC808014
- Price：Negotiable
- Clicks：251
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Mouse, Rat |
| Target | CREB-regulated transcription coactivator 2, CRTC2, TORC-2, TORC2, Transducer of CREB protein 2, Transducer of regulated cAMP response element-binding protein 2 |
| Immunogen | E. coli - derived recombinant CRTC2 (Gly621-Gln693). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q53ET0, Q3U182, Q3LRZ1 |
| Background | CREB-regulated transcription coactivator 2 is a ~73 kDa protein. Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. |
| Note | For research use only |
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