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Anti-Nipah virus/NiV F/Fusion glycoprotein F0 Recombinant Antibody

  • Cat. No.:RB9TVK521073
  • Price:Negotiable
  • Clicks:468

Product Detail

Product Parameters

FormLiquid
Host SpeciesMouse
ClonalityMonoclonal
IsotypeIgG2a, kappa
Purity>95% as determined by SDS-PAGE.
PurificationProtein A/G purified from cell culture supernatant.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, Neutralization
Species ReactivityNipah viurs
TargetF, Fusion glycoprotein F0, Fusion glycoprotein F1, Fusion glycoprotein F2, Protein F
Storage Buffer0.01M PBS pH 7.4
Stability and StorageUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Product Usage InformationELISA: 1:2000-1:20000
Accession NumberQ9IH63
Background

Fusion glycoprotein F0 (Fusion protein) is a ~60 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.

NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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