InVivoMAb anti-Mouse TIM-3 Antibody
- Cat. No.：RB9TMV029010
- Price：Negotiable
- Clicks：298
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rat |
| Clonality | Monoclonal |
| Isotype | IgG1, kappa |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin Level | < 10 EU/mg |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Species Reactivity | Mouse |
| Target | CD366, HAVcr-2, Havcr2, Hepatitis A virus cellular receptor 2 homolog, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, T |
| Storage Buffer | 0.01M PBS pH 7.4 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Product Usage Information | ELISA: 1:2000-1:20000 |
| Accession Number | Q8VIM0 |
| Background | Hepatitis A virus cellular receptor 2 homolog (CD366/HAVCR2) is a ~30 kDa protein. Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand. Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. 1. Anderson, AC. et al. (2007) Science (New York, N.Y.) 318, 1141-3. PMID: 18006747 2. Monney, L. et al. (2002) Nature 415, 536-41. PMID: 11823861 3. Sabatos, CA. et al. (2003) Nature immunology 4, 1102-10. PMID: 14556006 4. Lee, J. et al. (2011) Molecular and cellular biology 31, 3963-74. PMID: 21807895 5. Rangachari, M. et al. (2012) Nature medicine 18, 1394-400. PMID: 22863785 6. Jayaraman, P. et al. (2010) The Journal of experimental medicine 207, 2343-54. PMID: 20937702 7. Gorman, JV. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 3133-42. PMID: 24567532 8. DeKruyff, RH. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 184, 1918-30. PMID: 20083673 9. Nakayama, M. et al. (2009) Blood 113, 3821-30. PMID: 19224762 |
| Note | For research use only. |
Related Products:
| Product Name | Clicks |
|---|---|
| NGAL单克隆抗体 | 7752 |
| 白细胞介素6（IL-6）单克隆抗体 | 7491 |
| 肝素结合蛋白单克隆抗体 | 6790 |
| CRP单克隆抗体 | 7626 |
| 猫胰脂肪酶单克隆抗体 | 7429 |
| 马SAA单克隆抗体 | 7444 |
| 犬腺病毒单克隆抗体 | 6973 |
| 犬轮状病毒单克隆抗体 | 7045 |
| 犬血红蛋白单克隆抗体 | 7904 |
| 犬胰脂肪酶单克隆抗体 | 6944 |
| 犬松弛素单克隆抗体 | 7248 |
| 犬冠状病毒单克隆抗体 | 7350 |
| 犬瘟病毒单克隆抗体 | 6959 |
| 犬细小病毒单克隆抗体 | 7296 |
| 猫瘟病毒单克隆抗体 | 7684 |
| 猫疱疹病毒单克隆抗体 | 7210 |
| 猫杯状病毒单克隆抗体 | 7630 |
| 猫SAA单克隆抗体 | 7319 |
| 犬CRP单克隆抗体 | 7829 |
| 犬、猫IgG单克隆抗体 | 7244 |