Anti-TIMM23 Polyclonal Antibody
- Cat. No.：RB9THC876014
- Price：Negotiable
- Clicks：367
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Rat, Mouse |
| Target | Mitochondrial import inner membrane translocase subunit Tim23, TIM23, TIMM23 |
| Immunogen | E. coli - derived recombinant TIMM23 (Glu2-Arg72). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | O14925, O35093, Q9WTQ8, Q5SRD1 |
| Background | Mitochondrial import inner membrane translocase subunit Tim23 is a ~21 kDa protein. Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has a role in the activation of stress-induced mitophagy by protecting PINK1 from OMA1-mediated degradation and facilitating its accumulation at the outer mitochondrial membrane in response to depolarization. 1. Bauer, MF. et al. (1999) Journal of molecular biology 289, 69-82. PMID: 10339406 2. Akabane, S. et al. (2023) Cell reports 42, 112454. PMID: 37160114 |
| Note | For research use only |
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