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Anti-Human CD147/BSG Recombinant Antibody

  • Cat. No.:RB9THW664053
  • Price:Negotiable
  • Clicks:122

Product Detail

Product Parameters

FormLiquid
Host SpeciesHuman
ClonalityMonoclonal
IsotypeIgG4
Purity>95% as determined by SDS-PAGE.
PurificationProtein A/G purified from cell culture supernatant.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, FuncS
Species ReactivityHuman
Target5F7, BSG, Basigin, CD147, Collagenase stimulatory factor, EMMPRIN, Extracellular matrix metalloproteinase inducer, HAb18G, Hepatoma-associated antigen, Leukocyte activation antigen M6, OK blood group
Storage Buffer0.01M PBS pH 7.4
Stability and StorageUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Product Usage InformationELISA: 1:2000-1:20000
Accession NumberP35613
Background

Basigin (CD147/BSG) is a ~42 kDa protein. Essential for normal retinal maturation and development. Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes.

1. Aït-Ali, N. et al. (2015) Cell 161, 817-32. PMID: 25957687
2. Redzic, JS. et al. (2011) Journal of molecular biology 411, 68-82. PMID: 21620857
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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