| Host Species | HEK293T |
|---|---|
| Applications | FCM |
| Target | SARS-CoV-2 Nucleoprotein (N) |
| Stability and Storage | Frozen in liquid nitrogen. |
| Accession Number | P0DTC9 |
| Background | Nucleoprotein (SARS-CoV-2 Nucleoprotein (N)) is a ~45 kDa protein. Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Attenuates the stress granules formation by reducing host G3BP1 access to host mRNAs under stress conditions. 1. Dinesh, DC. et al. (2020) PLoS pathogens 16, e1009100. PMID: 33264373 2. Nabeel-Shah, S. et al. (2022) iScience 25, 103562. PMID: 34901782 3. Dolliver, SM. et al. (2022) PLoS pathogens 18, e1011041. PMID: 36534661 |
| Product Properties | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| Species | Viral (SARS-CoV-2) |