| Host Species | HEK293T |
|---|---|
| Applications | FCM |
| Target | SARS-CoV-2 Envelope small membrane protein (E) |
| Stability and Storage | Frozen in liquid nitrogen. |
| Accession Number | P0DTC4 |
| Background | Envelope small membrane protein (SARS-CoV-2 Envelope small membrane protein (E)) is a ~8 kDa protein. Plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Regulates the localization of S protein at cis-Golgi, the place of virus budding. May act by slowing down the cell secretory pathway. 1. Boson, B. et al. (2021) The Journal of biological chemistry 296, 100111. PMID: 33229438 2. De Maio, F. et al. (2020) Microbes and infection 22, 592-597. PMID: 32891874 |
| Product Properties | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| Species | Viral (SARS-CoV-2) |