HEK293T Human CD20/MS4A1 Stable Cell Line
- Cat. No.：RB9THY257818
- Price：Negotiable
- Clicks：386
Product Detail
Product Parameters
| Host Species | HEK293T |
|---|---|
| Applications | FCM |
| Target | CD20/MS4A1 |
| Stability and Storage | Frozen in liquid nitrogen. |
| Accession Number | P11836 |
| Background | B-lymphocyte antigen CD20 (MS4A1) is a ~33 kDa protein. B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. CD20 is the therapeutic target of rituximab (MabThera) and obinutuzumab (Gazyva). 1. Li, H. et al. (2003) The Journal of biological chemistry 278, 42427-34. PMID: 12920111 2. Tedder, TF. et al. (1985) Journal of immunology (Baltimore, Md. : 1950) 135, 973-9. PMID: 3925015 3. Bubien, JK. et al. (1993) The Journal of cell biology 121, 1121-32. PMID: 7684739 4. Polyak, MJ. et al. (2008) The Journal of biological chemistry 283, 18545-52. PMID: 18474602 |
| Product Properties | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| Species | Human |
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