| Host Species | HEK293T |
|---|---|
| Applications | FCM |
| Target | CD194/CCR4 |
| Stability and Storage | Frozen in liquid nitrogen. |
| Accession Number | P51679 |
| Background | C-C chemokine receptor type 4 (CD194/CCR4) is a ~41 kDa protein. High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. |
| Product Properties | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| Species | Human |