HEK293T Human CD158k/KIR3DL2 Stable Cell Line
- Cat. No.：RB9THW633818
- Price：Negotiable
- Clicks：311
Product Detail
Product Parameters
| Host Species | HEK293T |
|---|---|
| Applications | FCM |
| Target | CD158k/KIR3DL2 |
| Stability and Storage | Frozen in liquid nitrogen. |
| Accession Number | P43630 |
| Background | Killer cell immunoglobulin-like receptor 3DL2 (CD158k/KIR3DL2) is a ~50 kDa protein. Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity. 1. Goodridge, JP. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 191, 3553-62. PMID: 24018270 2. Dulberger, CL. et al. (2017) Immunity 46, 1018-1029.e7. PMID: 28636952 3. Song, S. et al. (2016) Nature medicine 22, 397-403. PMID: 26928464 |
| Product Properties | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| Species | Human |
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