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HEK293T Human CD158k/KIR3DL2 Stable Cell Line

  • Cat. No.:RB9THW633818
  • Price:Negotiable
  • Clicks:290

Product Detail

Product Parameters

Host SpeciesHEK293T
ApplicationsFCM
TargetCD158k/KIR3DL2
Stability and StorageFrozen in liquid nitrogen.
Accession NumberP43630
Background

Killer cell immunoglobulin-like receptor 3DL2 (CD158k/KIR3DL2) is a ~50 kDa protein. Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity.

1. Goodridge, JP. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 191, 3553-62. PMID: 24018270
2. Dulberger, CL. et al. (2017) Immunity 46, 1018-1029.e7. PMID: 28636952
3. Song, S. et al. (2016) Nature medicine 22, 397-403. PMID: 26928464
Product PropertiesGrowth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL)
SpeciesHuman
For Research Use Only. Not for Diagnostic Procedures.

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