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HEK293T Human CD112/Nectin-2/PVRL2 Stable Cell Line
- Cat. No.：RB9THV456818
- Price：Negotiable
- Clicks：186
Product Detail
Product Parameters
| Host Species | HEK293T |
|---|---|
| Applications | FCM |
| Target | CD112/Nectin-2/PVRL2 |
| Stability and Storage | Frozen in liquid nitrogen. |
| Accession Number | Q92692 |
| Background | Nectin-2 (CD112/PVRL2) is a ~57 kDa protein. Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. 1. Zhu, Y. et al. (2016) The Journal of experimental medicine 213, 167-76. PMID: 26755705 2. Warner, MS. et al. (1998) Virology 246, 179-89. PMID: 9657005 |
| Product Properties | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| Species | Human |
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