| Host Species | HEK293T |
|---|---|
| Applications | FCM |
| Target | SSTR2/SRIF-1 |
| Stability and Storage | Frozen in liquid nitrogen. |
| Accession Number | P30874 |
| Background | Somatostatin receptor type 2 (SSTR2/SRIF-1) is a ~41 kDa protein. Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. |
| Product Properties | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| Species | Human |