HEK293T Human VIPR1/VPAC1 Stable Cell Line
- Cat. No.：RB9THB111818
- Price：Negotiable
- Clicks：470
Product Detail
Product Parameters
| Host Species | HEK293T |
|---|---|
| Applications | FCM |
| Target | VIPR1/VPAC1 |
| Stability and Storage | Frozen in liquid nitrogen. |
| Accession Number | P32241 |
| Background | Vasoactive intestinal polypeptide receptor 1 (VIPR1/VPAC1) is a ~51 kDa protein. G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP). Binds VIP and both PACAP27 and PACAP38 bioactive peptides with the following order of ligand affinity VIP = PACAP27 > PACAP38. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway. 1. Xu, Y. et al. (2022) Nature communications 13, 2272. PMID: 35477937 2. Piper, SJ. et al. (2022) Nature communications 13, 7013. PMID: 36385145 3. Couvineau, A. et al. (1994) Biochemical and biophysical research communications 200, 769-76. PMID: 8179610 |
| Product Properties | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| Species | Human |
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