Anti-Human CD71/TFRC Recombinant Antibody
- Cat. No.：RB9THY036033
- Price：Negotiable
- Clicks：448
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, block |
| Species Reactivity | Human |
| Target | CD71, T9, TFRC, TR, TfR, TfR1, Transferrin receptor protein 1, Transferrin receptor protein 1, serum form, Trfr, p90, sTfR |
| Storage Buffer | 0.01M PBS pH 7.4 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Product Usage Information | ELISA: 1:2000-1:20000 |
| Accession Number | P02786 |
| Background | Transferrin receptor protein 1 (CD71/TFRC) is a ~84 kDa protein. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the hereditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. 1. Senyilmaz, D. et al. (2015) Nature 525, 124-8. PMID: 26214738 2. Jabara, HH. et al. (2016) Nature genetics 48, 74-8. PMID: 26642240 |
| Note | For research use only |
Related Products:
| Product Name | Clicks |
|---|---|
| 空肠弯曲菌单克隆抗体 | 7715 |
| 人触珠蛋白单克隆抗体 | 7801 |
| 贾第鞭毛虫单克隆抗体 | 7551 |
| 阿米巴单克隆抗体 | 7984 |
| 胃蛋白酶单克隆抗体 | 7546 |
| 胃蛋白酶原II单克隆抗体 | 7655 |
| 胃蛋白酶原I单克隆抗体 | 7499 |
| 艰难梭菌毒素A单克隆抗体 | 7564 |
| 艰难梭菌毒素B单克隆抗体 | 7980 |
| 艰难梭菌GDH单克隆抗体 | 7790 |
| 诺如病毒单克隆抗体 | 7407 |
| 伤寒沙门氏菌单克隆抗体 | 7600 |
| 鼠疫耶尔森菌F1单克隆抗体 | 6961 |
| 幽门螺杆菌单克隆抗体 | 7483 |
| 钙卫蛋白单克隆抗体 | 7327 |
| 乳铁蛋白单克隆抗体 | 7567 |
| 转铁蛋白单克隆抗体 | 7637 |
| 血红蛋白单克隆抗体 | 7386 |
| 腺病毒单克隆抗体 | 7563 |
| 轮状病毒单克隆抗体 | 7921 |