InVivo Plus Mouse CD161 Antibody(PK136)
- Cat. No.：RB9TMC598109
- Price：Negotiable
- Clicks：321
Product Detail
Product Parameters
| Product Description | The PK136 monoclonal antibody recognizes mouse NK1.1 (CD161b/CD161c, KLRB1, NKR-P1A), a type II membrane glycoprotein with a C-type lectin domain encoded by Klrb1c. NK1.1 functions in NK-cell activation, differentiation, IFN-γ production, and cytotoxic granule release, and is also expressed on a small NK-T cell subset. It is predominantly found as a disulfide-linked homodimer on NK cells. NK1.1 expression is strain-restricted, present in C57BL/6, FVB/N, and NZB mice, but absent in strains such as AKR, BALB/c, CBA/J, C3H, DBA, NOD, SJL, and 129. |
|---|---|
| Form | Liquid |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a, kappa |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin Level | <1 EU/mg |
| Applications | in vivo NK cell depletion, FCM |
| Species Reactivity | Mouse |
| Target | CLEC5B, KLRB1, CD161, HNKR-P1a, C-type lectin domain family 5 member B, NKRP1A, Natural killer cell surface protein P1A, Killer cell lectin-like receptor subfamily B member 1, NKR-P1A |
| Storage Buffer | 0.01M PBS, pH 7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Accession Number | P27811 |
| Note | For research use only. |
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