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InVivo Plus Mouse 4-1BB/TNFRSF9/CD137 Antibody(3H3)
- Cat. No.：RB9TMC336209
- Price：Negotiable
- Clicks：428
Product Detail
Product Parameters
| Product Description | 3H3 is an agonistic anti-4-1BB antibody that strongly enhances T-cell immunity. It boosts CD8+ T-cell activation, proliferation, and IFNg–mediated cytotoxicity, and also promotes NK-cell and Th1 responses. In vivo, 3H3 drives potent antitumor activity, increasing CD8+ T-cell infiltration and prolonging survival in tumor-bearing mice. Its therapeutic effect is CD8+ T-cell–dependent and supports the development of durable immune memory. |
|---|---|
| Form | Liquid |
| Host Species | Rat |
| Clonality | Monoclonal |
| Isotype | IgG2a, kappa |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin Level | <1 EU/mg |
| Applications | in vivo 4-1BB stimulation, in vitro 4-1BB stimulation |
| Species Reactivity | Mouse |
| Target | Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, T-cell antigen 4-1BB, CD137, Tnfrsf9, Ila, Ly63 |
| Storage Buffer | 0.01M PBS, pH 7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Accession Number | P20334 |
| Note | For research use only. |
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