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Research Grade Teriparatide

  • Cat. No.:RB9TSF921016
  • Price:Negotiable
  • Clicks:239

Product Detail

Product Parameters

FormLiquid
IsotypeBiosynthetic Parathyroid hormone (PTH) analogs.
Purity>95% as determined by HPLC.
PurificationPurified by HPLC.
Concentration1 mg/ml
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, Functional assay, Research in vivo
Species ReactivityHuman
TargetParathyroid hormone, Parathormone, PTH, Parathyrin
Storage Buffer0.01M PBS, pH 7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Accession NumberP01270
BackgroundTeriparatide is a portion of human parathyroid hormone (PTH), amino acid sequence 1 through 34, of the complete molecule (containing 84 amino acids). Endogenous PTH is the primary regulator of calcium and phosphate metabolism in bone and kidney. PTH increases serum calcium, partially accomplishing this by increasing bone resorption. Thus, chronically elevated PTH will deplete bone stores. However, intermittent exposure to PTH will activate osteoblasts more than osteoclasts. Thus, once-daily injections of teriparatide have a net effect of stimulating new bone formation leading to increased bone mineral density.
• Parathyroid hormone and its related peptides in bone metabolism., PMID:34224692
• Parathyroid hormone (PTH) regulation of metabolic homeostasis: An old dog teaches us new tricks., PMID:35338013
• MicroRNAs in parathyroid physiopathology., PMID:27816765
• Parathyroid hormone treatment partially reverses endplate remodeling and attenuates low back pain in animal models of spine degeneration., PMID:37967203
• PTH and cardiovascular risk., PMID:32192791
• Parathyromatosis., PMID:23128122
• Nephrogenic calcific arteriopathy., PMID:22143475
• Hypoparathyroidism and pseudohypoparathyroidism., PMID:17117292
• Structural pharmacology of PTH and PTHrP., PMID:35953106
• Parathyroid hormone for bone regeneration., PMID:29926970
Alternative Names52232-67-4
SpeciesHuman
NoteFor research use only. Not suitable for clinical or therapeutic use.
For Research Use Only. Not for Diagnostic Procedures.

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