InVivoMAb Anti-Rat CD198/CCR8 Antibody
- Cat. No.：RB9TRW444010
- Price：Negotiable
- Clicks：421
Product Detail
Product Parameters
| Product Description | CCR8, a receptor selectively expressed on activated Tregs within tumors, plays a key role in maintaining local immunosuppression. Iv0256 is a rat-reactive CCR8 antibody with improved functional potency. In CD34 humanized mice, Iv0256 markedly reduced HCC827 lung tumor growth after intravenous administration. In syngeneic LLC and H22 models, intraperitoneal Iv0256 also achieved robust tumor suppression, displaying a pronounced dose-response pattern across tested doses. |
|---|---|
| Form | Liquid |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a, kappa |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Concentration | 1 mg/ml |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, Neutralization |
| Species Reactivity | Rat |
| Target | C-C motif chemokine receptor 8, Ccr8 |
| Storage Buffer | 0.01M PBS, pH 7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Accession Number | D4ADE0 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
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