InVivoMAb anti-Mouse CCR8 Antibody
- Cat. No.：RB9TMW444010
- Price：Negotiable
- Clicks：161
Product Detail
Product Parameters
| Product Description | Iv0255 is an antibody that recognizes mouse CCR8, a chemokine receptor involved in recruiting and regulating immunosuppressive T cells in the tumor microenvironment. Iv0255 shows clear dose-dependent anti-tumor activity across multiple mouse models. In CD34 humanized mice, intravenous Iv0255 effectively inhibited the growth of HCC827 human lung cancer xenografts. In syngeneic models, intraperitoneal Iv0255 similarly suppressed tumor growth in both LLC lung cancer and H22 liver cancer. Higher doses consistently produced stronger tumor-volume inhibition. |
|---|---|
| Form | Liquid |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a, kappa |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Concentration | 1 mg/ml |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, Neutralization |
| Species Reactivity | Mouse |
| Target | C-C chemokine receptor type 8, C-C CKR-8, CC-CKR-8, CCR-8, CDw198, Ccr8, Cmkbr8, Ter1 |
| Storage Buffer | 0.01M PBS, pH 7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Accession Number | P56484 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
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