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InVivoMAb Anti-Chikungunya Virus/CHIKV VLP Antibody
- Cat. No.：RB9TVK425010
- Price：Negotiable
- Clicks：248
Product Detail
Product Parameters
| Product Description | m242 is a neutralizing monoclonal antibody against the Chikungunya virus E2 protein. As reported by Sun et al., eLife (2013), m242 binds the receptor-binding region of E2 and blocks viral attachment. The study demonstrates strong in vitro neutralization and indicates that m242 is suitable for use in in vivo CHIKV infection models. |
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| Form | Liquid |
| Host Species | Human |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Concentration | 1 mg/ml |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, Neutralization |
| Species Reactivity | Chikungunya virus |
| Target | Structural polyprotein, p130, Capsid protein, 3.4.21.90, Coat protein, C, Precursor of protein E3/E2, p62, pE2, Assembly protein E3, Spike glycoprotein E2, E2 envelope glycoprotein, 6K protein, Spike |
| Storage Buffer | 0.01M PBS, pH 7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Accession Number | Q8JUX5, Q1H8W5, Q5XXP3 |
| Background | Chikungunya virus (CHIKV) virus-like particles (VLPs) are non-infectious, self-assembled structures composed of viral structural proteins, typically E1, E2, and capsid, that mimic the morphology and antigenicity of native virions without containing viral RNA. CHIKV VLPs are widely used in vaccine development, serological assay design, and immunological studies, as they safely elicit robust immune responses and enable the evaluation of neutralizing antibodies. Their structural similarity to live virus makes them valuable tools for both basic research and translational applications in CHIKV prevention and diagnosti |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
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